A vascular closure device (200) includes a carrier tube (202), an anchor (208), a sealing pad (210), and a suture (204). The carrier tube defines a first lumen (268) and comprises a distal portion (260) and a proximal portion (262). The carrier tube is insertable through an insertion sheath (216). The anchor is positioned outside of the carrier tube. The sealing pad is positioned inside the first lumen. The suture couples the sealing pad to the anchor. The distal portion of the carrier tube has a different material composition from the proximal portion.