作為TRPM8拮抗劑的(4-羥基-2-苯基-1，3-噻唑-5-基)甲酮衍生物

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专利权人:

DOMPE' FARMACEUTICI S.P.A.;东佩制药股份公司

发明人:

ARAMINI, Andrea,BIANCHINI, Gianluca,LILLINI, Samuele,G‧比安基尼,LILLINI, Samuele,S‧利利尼

申请号：

HK19100257

公开号：

HK1257896B

申请日:

2019.01.08

申请国别(地区):

HK

年份:

2020

代理人:

摘要：

The invention relates to compounds acting as antagonists of Transient Receptor Potential cation channel subfamily M member 8 (TRPM8), and having formula (I): Said compounds are useful in the treatment of diseases associated with activity of TRPM8 such as pain, ischaemia, neurodegeneration, stroke, psychiatric disorders, itch, irritable bowel diseases, cold-induced and/or exacerbated- respiratory disorders, urological disorders, corneal disordes associated to disturbances in the production of the tears and/or altered blinking such as epiphora and dry eye disease.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/