Nicholas Scott Heaton,Alfred Theodore Harding,Brook Elizabeth Heaton
申请号：
US16317427
公开号：
US20190224305A1
申请日:
2017.07.12
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Engineered Influenza polynucleotides, viruses, vaccines, and methods of making and using the same are provided. More specifically, the present inventors have developed replication competent engineered influenza viruses having, for example, a modified segment 4 and/or segment 6 that include at least one additional polynucleotide encoding a heterologous polypeptide.
