A method includes providing a guide block with a body having a proximal face, a distal face, a length between the proximal and distal faces, a central longitudinal axis extending between the proximal and distal faces, and at least one passageway disposed within the body that extends between the proximal and distal faces, which is configured to receive a tissue accessing device and which is not parallel to the central longitudinal axis； selecting a grid opening of the grid-like breast receiving pressure plate and selecting a rotational orientation of the guide block relative to the selected grid opening to provide access to a desired location in the patient's breast； and inserting the guide block into the selected grid opening of the grid-like breast receiving pressure plate of the magnetic resonance imaging device at the selected rotational orientation, and advancing the guide block in the selected grid opening.
