A magnetic resonance imaging system may include a magnet, gradient coils, an RF pulse transmitter, an RF receiver that receives MR signals from tissue that has been exposed to RF pulses, gradient fields, and a magnetic field, and a computer that includes a processor. The computer may have a configuration that: causes the RF pulse transmitter and gradient coils to emit multiple labeling pulses at predetermined labeling times directed to blood in a subject causes the RF pulse transmitter, gradient coils, and magnet to generate MR signals directed to tissue at one or more spatial locations within the subject that receives the blood causes the RF receiver to receive MR signals emitted by the tissue at predetermined imaging times generates an image of the tissue based on the received MR signals repeats the foregoing four actions one or more times and generates information indicative of perfusion within the tissue based on the generated images.
