A surgical instrument includes an end effector, a handle assembly, and a latch assembly. The end effector includes a first jaw, a second jaw pivotably coupled with the first jaw, a knife, and an electrode assembly. The handle assembly includes a housing associated with the first jaw, and an arm associated with the second jaw. The arm can pivot the second jaw between an open position and a closed position. The latch assembly can transition between an unlatched configuration and a latched configuration. The latch assembly can prevent the arm from pivoting the second jaw from the closed position toward the open position in the latched configuration. The latch assembly can allow the arm to pivot the second jaw from the closed position toward the open position in the unlatched configuration.