HELMHOLTZ ZENTRUM MÜNCHEN-DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH);SIRION BIOTECH GMBH
发明人:
Natasa Anastasov,Ines Höfig,Christian Thirion
申请号：
US14381586
公开号：
US09771599B2
申请日:
2013.02.28
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention relates to a method for transducing a target cell, the method comprising the step of contacting a target cell with a retroviral vector and a poloxamer having a molecular weight of 12.8 kDa to about 15 kDa. Further, the invention relates to the use of a poloxamer as defined herein, optionally in combination with a polycationic substance as defined herein, for transducing a target cell with a retroviral vector and a kit comprising a retroviral vector, a poloxamer as defined herein and, optionally, instructions for use.
