Disclosed herein, are compositions comprising one or more therapeutic agents non-covalently conjugated to a nanomaterial (e.g., graphene oxide). Also, described herein, are methods of preparing stable compositions, the methods comprising a plurality of antibodies non-covalently bound to graphene oxide physiologically acceptable compositions including them and methods of administering the compositions to patients for the treatment of a disease such as cancer and autoimmune disorders as well as for the prevention of graft rejection.