Mark Leo Michaels;Jeonghoon Sun;Lei-Ting Tony Tam;Rohini Deshpande;Yue-Sheng Li;Thomas C. Boone;Hq Han
发明人:
Jeonghoon Sun,Lei-Ting Tony Tam,Mark Leo Michaels,Thomas C. Boone,Rohini Deshpande,Yue-Sheng Li,Hq Han
申请号：
US12626375
公开号：
US08410043B2
申请日:
2009.11.25
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention provides stabilized activin IIB receptor polypeptides and proteins capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the stabilized polypeptides and proteins. Compositions and methods for treating muscle-wasting diseases and metabolic disorders are also provided.
