DELANEY JOHN M.,FANSLOW WILLIAM CHRISTIAN III,KING CHADWICK TERENCE
申请号:
NZ62271112
公开号:
NZ622711A
申请日:
2012.09.20
申请国别(地区):
NZ
年份:
2016
代理人:
摘要:
Disclosed is a CD27L antigen binding protein having a light chain variable domain comprising an LCDR1 having no more than three amino acid additions, deletions, or substitutions from the LCDR1 sequence set forth in RSSQSLLNSNGYNYLD an LCDR2 having no more than two amino acid additions, deletions, or substitutions from the LCDR2 sequence set forth in LGSYRAS and an LCDR3 having no more than two amino acid additions, deletions, or substitutions from the LCDR3 sequence set forth in IQTLQTPFT and a heavy chain variable domain comprising an HCDR1 having no more than one amino acid addition, deletion, or substitution from the HCDR1 sequence set forth in NYGIH an HCDR2 having no more than three amino acid additions, deletions, or substitutions from the HCDR2 sequence set forth in VIWYDGSNKYYADSVKG and an HCDR3 having no more than three amino acid additions, deletions, or substitutions from the HCDR3 sequence set forth in DGGYSGYDSGFDY.