Mayo Foundation for Medical Education and Research
发明人:
James L. Kirkland,Tamar Tchkonia,Yi Zhu,Allyson K. Palmer,Nathan K. LeBrasseur,Jordan D. Miller
申请号：
US15113723
公开号：
US20170216286A1
申请日:
2015.01.28
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Provided herein are methods and uses for treatment or prophylaxis of a senescent cell associated disease or disorder by administering a senolytic combination comprising dasatinib and quercetin or an analog thereof to a subject in need thereof. In certain embodiments, the senescent cell associated disease or disorder is a cardiovascular disease or disorder, inflammatory disease or disorder, a pulmonary disease or disorder, a neurological disease or disorder, or a metabolic disease or disorder.
