Nucleic acids molecule encoding the polypeptide for treating virus-induced cancer

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专利权人:

发明人:

Xiao-Qing Qiu

申请号：

US13708754

公开号：

US08802837B2

申请日:

2012.12.07

申请国别(地区):

US

年份:

2014

代理人:

摘要：

The present invention relates to nucleic acid molecules encoding the polypeptides that are capable of killing tumor cells. The molecules comprise a targeting agent covalently attached to a channel-forming moiety. In a preferred embodiment, the channel-forming moiety comprises a colicin and the targeting agent is a reconstructed antibody mimetic derived from monoclone antibody against Epstein-Barr virus gp350/220.

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