Anna HULTBERG,Michael SAUNDERS,Johannes DE HAARD,Els FESTJENS,Natalie DE JONGE,Paulo MICHIELI
申请号:
US15596890
公开号:
US20170349667A1
申请日:
2017.05.16
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention provides a product combination or composition, and also multispecific antibodies comprising two or more antigen-binding sites (as antibodies or antigen binding fragments thereof), wherein two the antigen-binding bind to distinct non-overlapping epitopes of the human c-Met protein. The product combination or composition or multispecific antibody inhibits HGF-independent activation of the human c-Met receptor protein.