Medical device packaging, medical device packaging assemblies, and methods for preparing and packaging medical devices. An example medical device packaging assembly may include a packaging pouch including a front pouch portion and a back pouch portion. The front pouch portion may include a first sheet of material having a plurality of layers. The back pouch portion may include a second sheet of material having a plurality of layers. A medical device may be disposed in the pouch. At least one of the plurality of layers of first sheet of material and the plurality of layers of second sheet of material may include a moisture scavenging layer. In addition, at least one of the plurality of layers of first sheet of material and the plurality of layers of second sheet of material may include a barrier layer that is configured to maintain the oxygen concentration within the packaging pouch.