STABILIZATION OF LIQUID SOLUTIONS OF RECOMBINANT PROTEIN FOR FROZEN STORAGE

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专利权人:

BAYER HEALTHCARE; LLC

发明人:

TSVETKOVA, NELLY,JOSHI, OMKAR,WU, PAUL,WANG, DEQIAN,DESPONDS, ARNAUD

申请号：

EP08746549

公开号：

EP2150264A4

申请日:

2008.04.22

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

The invention relates to a method for stabilizing a bulk solution of recombinant protein for frozen storage, which comprises providing a partially-purified solution of recombinant protein which has a monovalent salt concentration of at least 100 mM, and adding a carbohydrate to said solution in an amount sufficient that, upon freezing, the solution has a glass transition temperature of &minus56° C. or higher.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/