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STABILIZATION OF LIQUID SOLUTIONS OF RECOMBINANT PROTEIN FOR FROZEN STORAGE
专利权人:
BAYER HEALTHCARE; LLC
发明人:
TSVETKOVA, NELLY,JOSHI, OMKAR,WU, PAUL,WANG, DEQIAN,DESPONDS, ARNAUD
申请号:
EP08746549
公开号:
EP2150264A4
申请日:
2008.04.22
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
The invention relates to a method for stabilizing a bulk solution of recombinant protein for frozen storage, which comprises providing a partially-purified solution of recombinant protein which has a monovalent salt concentration of at least 100 mM, and adding a carbohydrate to said solution in an amount sufficient that, upon freezing, the solution has a glass transition temperature of &minus56° C. or higher.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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