An interventional medical device is provided that incorporates a forward-directed ultrasound imaging system integrated into a single minimally invasive device. The medical device can be in the form of catheters and interventional devices having a tapered distal tip, particularly those suitable for minimally invasive direct introduction into the human or other mammalian body. The imaging system comprises one or more small ultrasound transducers that can be permanently integrated into the device or integrated into an interchangeable ultrasound transducer that may be inserted into and removed from the device to customize the device for a particular use. An ultrasound system can be provided in the device either alone or in combination with fiber optic imaging to provide a range of forward imaging and therapeutic capabilities of the device for direct access to a target site from the skin via an introducer needle.
