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FORME DOSIFIÉE NON INTRAVEINEUSE COMPRENANT UNE FORMULATION SOLIDE D'UN AGENT LIQUIDE BIOLOGIQUEMENT ACTIF ET SES UTILISATIONS
专利权人:
PALADIN LABS INC.;PALADIN LABS EUROPE LIMITED;PALADIN LABS (BARBADOS) INC.
发明人:
RAVENELLE, FRANCOIS,LE GARREC, DOROTHEE,LESSARD, DAVID,GORI, SANDRA,SMITH, DAMON,RAHMOUNI, MILOUD,SANT, VINAYAK
申请号:
EP11771439
公开号:
EP2563349A4
申请日:
2011.04.21
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
The disclosure relates to a non-intravenous dosage for administration of a liquid biologically active agent. The dosage form contains a solid formulation of the liquid biologically active agent, e.g. propofol, in intimate association with at least one stabilizing agent, e.g. an amphiphilic polymer or surfactant. A liquid biologically active agent is converted to a solid product, e.g. a powder, that can be easily incorporated into a number of different non-intravenous dosage forms. Upon hydration, a nanodispersion or micelle loaded with the active agent is formed. The dosage form can provide a non-intravenous route of administration for active agents that are typically only administered intravenously. Methods, uses, kits and commercial packages related to the non-intravenous dosage form are also disclosed.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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