Fibronectin type III domain-based multimeric scaffolds

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专利权人:

LLC;MedImmune

发明人:

Baca, Manuel,Thisted, Thomas,Swers, Jeffrey

申请号：

AU2011240620

公开号：

AU2011240620A1

申请日:

2011.04.12

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

The present invention provides fibronectin type III (Fn3)-based multimeric scaffolds that specifically bind to one or more specific target antigen. The invention further provides bispecific Fn3-derived binding molecules that bind to two or more target antigens simultaneously, fusions, conjugates, and methods to increase the stability of Fn3-based binding molecules. Furthermore, the present invention is related to a prophylactic, therapeutic or diagnostic agent, which contains Fn3-based multimeric scaffolds.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/