PTCHELINTSEV, DMITRI S.,LUO, XIAOCHUN,CHEN, SIMING W.
申请号：
CA2708538
公开号：
CA2708538C
申请日:
2008.11.19
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Topical compositions and methods of use to treat symptoms of reduced skinelasticity are provided comprisingdesthiobiotin and certain desthiobiotin analogues. These compounds areeffective in stimulating LOXL-1 activity and can thusincrease elastin remodeling and improve appearance of fine lines, wrinkles,skin sagging and other symptoms of reduced elastinfunction.
