Tommaso Mansi,Saikiran Rapaka,Ali Kamen,Dorin Comaniciu,Francois Forlot,Liexiang Fan
申请号:
US14693080
公开号:
US09814446B2
申请日:
2015.04.22
申请国别(地区):
US
年份:
2017
代理人:
摘要:
A method and system for automatic non-invasive estimation of shear modulus and viscosity of biological tissue from shear-wave imaging is disclosed. Shear-wave images are acquired to evaluate the mechanical properties of an organ of a patient. Shear-wave propagation in the tissue in the shear-wave images is simulated based on shear modulus and viscosity values for the tissue using a computational model of shear-wave propagation. The simulated shear-wave propagation is compared to observed shear-wave propagation in the shear-wave images of the tissue using a cost function. Patient-specific shear modulus and viscosity values for the tissue are estimated to optimize the cost function comparing the simulated shear-wave propagation to the observed shear-wave propagation.