Uri HERZBERG,Qian YE,Aleksandr KAPLUNOVSKY,Mohit B. BHATIA,Raihana ZAKA
申请号:
MX2017002469
公开号:
MX2017002469A
申请日:
2015.08.25
申请国别(地区):
MX
年份:
2017
代理人:
摘要:
Provided herein are placental extracellular matrix (ECM) compositions and methods of making the same. Also provided herein are uses of the placental ECM compositions provided herein. In one aspect, provided herein are extracellular matrix (ECM) compositions prepared using placental tissue, e.g., human placental tissue. In certain embodiments, the ECM compositions provided herein comprise about 30% to about 60% collagen and about 10% to about 35% elastin. In addition, such ECM compositions comprise (i) very low amounts of fibronectin (e.g., less than 0.1% fibronectin), e.g., as measured by ELISA (ii) no or an undetectable amount of laminin, e.g., as measured by ELISA and/or no or an undetectable amount of glycosaminoglycans, e.g., as measured by ELISA.Se proporcionan aquí composiciones de matriz extracelular placentaria (CME) y métodos para fabricarlas. También se proporcionan usos de las composiciones placentarias CME proporcionadas en la presente memoria.