A compound represented by the following general formula (A-1) and general formula (1) or a salt thereof is provided. Since the compound of the general formula (A-1) and the general formula (1) or a salt thereof has a β3 adrenergic receptor agonistic action, it is derived from diabetes, obesity, hyperlipidemia, depression, gallstones, increased biliary motility It is useful as a therapeutic and preventive agent for diseases such as those caused by hypergastrointestinal function, interstitial cystitis, overactive bladder or urinary incontinence, or a disease associated with a decrease in tears.下記一般式（Ａ－１）及び一般式（１）で示される化合物又はその塩が提供される。一般式（Ａ－１）及び一般式（１）の化合物又はその塩は、β3アドレナリン受容体アゴニスト作用を有するので、糖尿病、肥満症、高脂血症、うつ病、胆石、胆道運動亢進に由来する疾患、消化管機能亢進に由来する疾患、間質性膀胱炎、過活動膀胱又は尿失禁などの治療及び予防剤、或いは涙液の減少に伴う疾患の治療及び予防剤として有用である。
