PROBLEM TO BE SOLVED: To provide skin penetration promoting agents having good skin compatibility, a good feeling of use and low skin irritation, as well as high skin penetration promoting effect to poorly water soluble substances, and to provide skin external preparations containing the same.SOLUTION: The present invention provides a skin penetration promoting agent for poorly water soluble substances, the skin penetration promoting agent containing mannosyl erythritol lipid as an active ingredient.SELECTED DRAWING: NoneCOPYRIGHT: (C)2017,JPO&INPIT【課題】本発明は、肌なじみがよく、良好な使用感をもち、かつ皮膚への刺激が低い皮膚浸透促進剤であって、難水溶性物質に対し高い皮膚促進効果を有する皮膚浸透促進剤、及びこれらを含有する皮膚外用剤を提供することを目的とする。【解決手段】マンノシルエリスリトールリピッドを有効成分として含有する難水溶性物質の皮膚浸透促進剤。【選択図】なし