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Fc VARIANTS
专利权人:
AMGEN INC.
发明人:
Zhi LIU,Gunasekaran KANNAN,Wei YAN
申请号:
US16413810
公开号:
US20200010545A1
申请日:
2019.05.16
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed are Fc-containing proteins comprising a binding region and a variant Fc region that can elicit one or more immune effector function and/or bind to an Fc receptor more effectively than a similar Fc-containing protein comprising a wild type Fc region. Also disclosed are nucleic acids encoding such Fc-containing proteins, methods for making such proteins, and methods of treatment utilizing such proteins.
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