Anti FcRn Antibody； sequences that encode； vector； host Cell； production process； Pharmaceutical composition containing same and use for the treatment of autoimmune disease； and trial to test the ability of an Antibody to block the activity of Human FcRn.
FINNEY HELENE MARGARET,LAWSON ALASTAIR DAVID GRIFFIFHS,SHAW STEVAN GRAHAM,SMITH BRYAN JOHN,TYSON KERRY LOUISE,KEVORKIAN LARA,MEIER CHRISTOPH,ATHERFOLD PAUL ALAN,SARKAR KAUSHIK
申请号：
CL2014003110
公开号：
CL2014003110A1
申请日:
2014.11.14
申请国别(地区):
CL
年份:
2015
代理人:
摘要：
The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.UN ANTICUERPO ANTI-FCRN CA170_01519, EN SU VERSION PEGILADA COMO SOLA, DE ALTA AFINIDAD TANTO A PH ACIDO COMO NEUTRO, QUE INHIBE LA ACTIVIDAD DE FCRN EVITANDO EL RECICLAJE DE IGG.
