Paul Anthony Macary,Conrad En Zuo Chan,Brendon John Hanson,Markus R. Wenk
申请号:
US13981442
公开号:
US09315566B2
申请日:
2012.01.25
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Described herein are antigen binding proteins that bind to pathogenic mycobacteria-derived Mannose-Capped Lipoarabinomannan (ManLAM) and methods and kits for using and making the antigen binding proteins. Also described herein are antigen binding proteins that bind to the alpha 1-2 linkage mannose caps of ManLAM, antigen binding proteins that bind to a mannose cap with up to three alpha 1-2 linked mannose residues, and antigen binding proteins that bind to LAM with a mannose sugar capping motif.