Universidade Federal de São Paulo - UNIFESP;Cryopraxis Criobiologia LTDA.;University Of South Florida
发明人:
申请号：
EP09813763.1
公开号：
EP2331679B1
申请日:
2009.09.14
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
The present invention is directed to compositions and methods for treatment of ischemic diseases and conditions, particularly myocardial, CNS/brain and limb ischemia. More particularly, the present invention provides methods of treating disorders by administering monocytes obtained from blood, including umbilical cord blood, peripheral blood, or bone marrow to an individual in need of treatment, wherein the drug is administered to the individual at a time point specifically determined to provide therapeutic efficacy. In one embodiment, the cells are for injection into ischemic myocardium for the treatment of angina.
