The present invention relates to a process for preparing 4-{4-[({[4-chloro-3-(trifluoromethyl)-phenyl]amino}carbonyl)amino]-3-fluorophenoxy}-N-methylpyridine-2-carboxamide, its salts and monohydrate.本發明係關於一種製備4-{4-[({[4-氯-3-(三氯甲基)-苯基]胺基}羰基)胺基]-3-氟苯氧基}-N-甲基吡啶-2-甲醯胺、其鹽及單水合物之方法。