ROSS RUTH ALEXANDRA,ROGERS MICHAEL JOHN,FORD LESLEY ANN,ROELOFS ANKE JOZEFIEN
申请号：
IN8511/DELNP/2010
公开号：
IN2010DN08511A
申请日:
2010.11.30
申请国别(地区):
IN
年份:
2013
代理人:
摘要：
The present inventors demonstrate that the G-protein coupled receptor 55 (GPR55) is highly expressed in human aggressive breast cancer cells, and that the expression level may be correlated with the invasiveness and metastatic potential of these cells (for example metastasis to bone). In various aspects of the invention there are disclosed diagnostic tools or biomarkers that relate to the metastatic profile of breast cancer tumours. The invention also relates to pharmacological agents targeting this receptor for the purposes of inhibiting progression and spread of breast cancer.
