Provided are compositions with Pesticide activity and Methods of Use thereof.The compositions include isolated polypeptides and recombinant molecules possess Pesticide activity, Nucleic Acids encoding the recombinant and Synthetic polypeptides, DNA constructs and vectors comprising the Nucleic Acid Molecules, host cells which com On the vectors, and Antibodies to the polypeptides.The nucleotide sequences that Encode the polypeptides can be used in DNA constructs or expression cassettes for Transformation and expression in organisms of interest. The compositions and methods are useful for production provided the agencies with a better resis Competition or tolerance to pests.Also provided are transgenic plants and Seeds comprising a Nucleotide sequence that encodes a Protein of this Pesticide. Such plants are resistant to insects and other pests. Provided are methods for the production of the various polypeptides described herein, and to the use of these polypeptides in the control or elimination of a Pest.Also included are methods and Kits for the detection of polypeptides in a sample. The Method of claim 22: 21 Claims, which the plant produces a polypeptide that possesses Pesticide Pesticide activity against a Pest of Lepidoptera, Coleoptera and Hemiptera.Se proveen composiciones con actividad pesticida y métodos de uso de las mismas. Las composiciones incluyen polipéptidos aislados y recombinantes que poseen actividad pesticida, moléculas de ácidos nucleicos recombinantes y sintéticos que codifican los polipéptidos, construcciones de ADN y vectores que comprenden las moléculas de ácido nucleico, células huésped que comprenden los vectores, y anticuerpos para los polipéptidos. Las secuencias de nucleótidos que codifican los polipéptidos se pueden utilizar en construcciones de ADN o casetes de expresión para la transformación y expresión en organismos de interés. Las composiciones y métodos provistos son útiles para la producción de organismos con una mejor resistenc
