Stable formulation of growth hormone comprising lactate anion

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专利权人:

Jan Jezek

发明人:

Jan Jezek

申请号：

US12851295

公开号：

US08796210B2

申请日:

2010.08.05

申请国别(地区):

US

年份:

2014

代理人:

摘要：

An aqueous composition comprising a therapeutic protein further characterized in that(i) the pH of the composition is adjusted to be between about 5.9 and 6.3, preferably about 6.1(ii) the composition comprises at least one displaced buffer having a pKa within 1 to 3 pH units of the pH of the composition(iv) the osmolarity of the composition is between 150-500 mOsm/L.

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