A composition comprising a population of non-immunogenic amnion-derived multipotent progenitor cells (AMP cells) that are epithelial cells that are positive for cytokeratin expression and negative for CD34 expression, in which the population of non-immunogenic AMP cells that are epithelial cells are prepared by the method of: (a) dissociating AMP cells that are epithelial cells from an amniotic membrane of an amnion isolated from a placenta； (b) harvesting the dissociated AMP cells that are epithelial cells； and (c) culturing the collected AMP cells that are epithelial cells in culture medium that contains no animal derived materials other than human proteins； wherein non-immunogenic AMP cells are for use in suppressing, preventing, or enhancing an immune response in a subject who could benefit from it； and in which the immune response: (a) is an autoimmune response such as Type I diabetes, multiple sclerosis, systemic lupus erythematosus, Grave's disease, autoimmune hemolytic anemia, bullous pemphigoid, Hashimoto's thyroiditis, myasthenia gravis, pemphigus, or anemia pernicious； or (b) is an allogeneic response such as graft-versus-host disease or host-graft disease.Una composición que comprende una población de células progenitoras multipotentes derivadas del amnios no inmunogénicas (células AMP) que son células epiteliales que son positivas para la expresión de citoqueratinas y negativas para la expresión de CD34, en la que la población de células AMP no inmunogénicas que son células epiteliales se prepara con el método de: (a) disociar células AMP que son células epiteliales de una membrana amniótica de un amnios aislado de una placenta； (b) recoger las células AMP disociadas que son células epiteliales； y (c) cultivar las células AMP recogidas que son células epiteliales en medio de cultivo que no contiene materiales derivados de animal distintos de proteínas humanas； en la que las células AMP no inmunogénicas son para su uso en la supresión, prevención o mejor
