The present invention relates to a cosmetic composition based on iron ion (Fe2+ and/or Fe3+) chelating agents and the use thereof for the non-surgical treatment of lipodystrophies and of so-called "cellulite". In particular, the composition of the present invention comprises at least one Fe2+ and/or Fe3+ ion chelating agent, at least one osmotic diuretic, at least one amino acid and at least one vitamin. Said composition makes it possible to considerably improve the aesthetic appearance of areas of the body, in particular the lower limbs, affected by an accumulation and structural alteration of adipose tissue. In fact, the degree of satisfaction of the subjects who underwent the cosmetic treatment of the present invention is high.
