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METHOD OF ADMINISTRATION AND TREATMENT
专利权人:
发明人:
Diptee Amit KULKARNI,Colin F Spraggs
申请号:
US14173973
公开号:
US20140221372A1
申请日:
2014.02.06
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention is directed to methods of administering foretinib or pharmaceutically acceptable salts or solvates thereof a c-Met inhibitor to a patient in need thereof comprising:determining whether said patient has less than 2 copies of the CAT haplotype in NR1I3 gene and/or the TT or CT genotype at the rs1045642 reference single nucleotide polymorphism in ABCB1 gene andif said patient has less than 2 copies of the CAT haplotype in NR1I3 gene and/or the TT or CT genotype at the rs1045642 reference single nucleotide polymorphism in ABCB1 gene, administering to said patient a pharmaceutical composition comprising foretinib or a pharmaceutically acceptable salt thereof.
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