The present invention relates to a medicament delivery device comprising a tubular housing a needle shield sleeve (20) a syringe carrier mechanism comprising a syringe carrier (36), a syringe (16), a holding member (46), a first activator member (56) , a second activator member (66), a drive mechanism comprising a plunger rod (90) wherein the second activator member (66) comprises flexible tongues (70) having annular inwardly directed ledges (74), wherein the holding member (46) comprises flexible tongues (52) having ledges (54), and wherein the plunger rod (90) comprises a circumferential groove (96) having a mutual shape as that of the ledges (74) of the second activator member (66) and as that of the ledges (54) of the holding member (46) so that the annular inwardly directed ledges (74) of the second activator member (66) and the radial inwardly directed ledges (54) of the holding member fit into the groove (96).