This discloses a device (10) for closure of an opening in a medical patients subcutaneous tissue wall. The devices (10) includes a catheter (20) having one or more inflatable, bio-degradable balloons (30, 40) and one or more sheets (50, 60) of ECM material loaded on and around said catheter (20). Upon inflation of the one or more balloons (30, 40) the sheet(s) of ECM material are held against the tissue wall by the balloons. Surgical methods using the device are also disclosed.