John P. Toscano,Art Sutton,Vincent J. Kalish,Frederick Arthur Brookfield,Stephen Martin Courtney,Lisa Marie Frost
申请号:
US12962544
公开号:
US09018411B2
申请日:
2010.12.07
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The invention provides certain bis-acylated hydroxylamine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the invention provides methods of using such compounds or pharmaceutical compositions for treating, preventing, or delaying the onset and/or develop of a disease or condition. In some embodiments, the disease or condition is selected from cardiovascular diseases, ischemia, reperfusion injury, cancerous disease, pulmonary hypertension and conditions responsive to nitroxyl therapy.