您的位置: 首页 > 农业专利 > 详情页

Crystalline form of BTK kinase inhibitor and preparation method thereof
专利权人:
Jiangsu Hengrui Medicine Co.; Ltd.
发明人:
Wu, Guaili,Qiu, Zhenjun,Lu, Xi,Lu, Yun
申请号:
AU2016384921
公开号:
AU2016384921A1
申请日:
2016.12.20
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The present invention relates to a crystalline form of a BTK kinase inhibitor and the preparation method thereof. In particular, the present invention relates to a type I crystal of (R)-1-(3-(4-amino-3-(4-(2,6-difluorophenoxy)phenyl)-7-hydroxy-1H-pyrorolo[2,3-d]pyridaz-1-yl)pyrrolidin-1-yl)butyl-2-alkyne-1-ketone (the compound in formula (I)) and the preparation method thereof. The type I crystal of the compound of formula (I) obtained by the present invention has a good crystal stability and chemical stability, and the crystal solvent used has a low toxicity and residue, thus making same more suitable for use in clinical treatment.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
相关发明人
相关专利

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充