Minhua Chen,Yanfeng Zhang,Chaohui Yang,Xiaoyu Zhang,Peng Wang,Pixu Li,Fei Lu,Heng Ge
申请号：
US15100247
公开号：
US09751889B2
申请日:
2014.11.26
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Crystalline Form I of ibrutinib, processes for its preparation, pharmaceutical compositions comprising the new Form, and use of Form I of ibrutinib for treating or delaying diseases or disorders related to activity of Brutons tyrosine kinase (BTK) proteins are disclosed. The novel Form was characterized by X-ray powder diffraction, differential scanning calorimetry, and other techniques. It can be readily prepared and is suitable for use in the preparation of solid dosage forms.
