A device (1) for organic tissutal re-conditioning comprises a support layer (2) associable with organic tissues, in particular vascularised tissues and still more particularly human male and/or female genitals a plurality of light radiation sources (3) disposed on the support layer (2) and adapted to face the organic tissues to enable them to be irradiated, each source (3) being designed to emit radiation in a respective major frequency and according to a respective predetermined time interval a control box associated with the sources (3) for controlling switching on and/or off of each source (3) according to a predetermined sequence and stimulating the organic tissues.