George Heavner,David M. Knight,Jill Giles-Komar,Bernard Scallon,David Shealy
申请号:
US14068010
公开号:
US09321836B2
申请日:
2014.02.18
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to anti-TNF antibodies comprising all of the heavy chain variable CDR regions of SEQ ID NOS: 1, 2 and 3 and/or all of the light chain variable CDR regions of SEQ ID NOS:4, 5 and 6, specific for at least one human tumor necrosis factor alpha (TNF) protein or fragment thereof, as well as nucleic acids encoding such anti-TNF antibodies, complementary nucleic acids, vectors, host cells, production methods and therapeutic methods.