The particle beam irradiation room of the invention includes: an irradiation execution room in which a patient table having a detachable-attachable top board and an actuation device for actuating the top board is mounted, and that is surrounded by a shielding wall; a passage formed in the shielding wall on its side where a pre-room for positioning the patient relative to the top board is located, in a form that allows the patient positioned relative to the top board to pass straight to the irradiation execution room by a transport apparatus; and a shielding door at the irradiation-room entrance located on a side of the passage toward the pre-room, for shielding against a leakage radiation at the radiation of the particle beam so that the leakage radiation is kept at a management value or less.