CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S);UNIVERSITE D'ORLEANS
发明人:
QUESNIAUX RYFFEL, VALERIE,MARTIN, OLIVIER,FRONT, SOPHIE
申请号:
EP09765996.5
公开号:
EP2280986B1
申请日:
2009.05.20
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The present invention relates to novel synthetic analogs of phosphatidyl-myo-inositol mannosides (hereinafter referred to as PIMs) of general formula (I): or a pharmaceutically acceptable salt thereof, to the method for preparing same and to the use thereof in the prevention or treatment of a disease associated with the overexpression of cytokines or of chemokines, in particular of TNF and/or of IL-12. The invention also relates to a pharmaceutical composition comprising at least one synthetic derivative of PIM.