According to the invention, there is provided a novel soybean variety designated XB22B08. This invention thus relates to the seeds of soybean variety XB22B08, to the plants of soybean XB22B08 to plant parts of soybean variety XB22B08 and to methods for producing a soybean plant produced by crossing plants of the soybean variety XB22B08 with another soybean plant, using XB22B08 as either the male or the female parent.