TETRACYCLIC HETEROCYCLE COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES农业专利-农业学术服务平台

发明人:: SOLL, RICHARD,索尔理查,索爾理查,MCCOMAS, CASEY C.,麦可曼斯凯西C,麥可曼斯凱西C,LIVERTON, NIGEL J.,利佛敦奈吉尔J,利佛敦奈吉爾J,PENG, XUANJIA,彭宣嘉,彭宣嘉,WU, HAO,吴颢,吳顥,HABERMANN, JOERG,贺伯曼裘格,賀伯曼裘格,KOCH, UWE,科奇乌威,科奇烏威,NARJES, FRAN

摘要：: The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.本發明係關於一種適用作C型肝炎病毒(HCV)NS5B聚合酶抑制劑之式(I)化合物,該等化合物之合成,及該等化合物用於抑制HCV NS5B聚合酶活性、用於治療或預防HCV感染及用於在基於細胞之系統中抑制HCV病毒複製及/或病毒產生的用途。