Frédéric PILOTAZ,Alan L. WEINER,Marina DO,Julien SALDO
申请号:
US16508028
公开号:
US20200016108A1
申请日:
2019.07.10
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention provides aqueous ophthalmic compositions in the form of solution comprising hexanoic acid, 6-(nitrooxy)-, (1S,2E)-3-[(1R,2R,3S,5R)-2-[(2Z)-7-(ethylamino)-7-oxo-2-hepten-1-yl]-3,5-dihydroxycyclopentyl]-1-(2-phenylethyl)-2-propen-1-yl ester and macrogol 15 hydroxystearate as the only solubilizing agent, and a method for their preparation.