The present invention relates to be used for Naftazone or a kind of its purposes of the pulse release of pharmaceutically acceptable salt comprising Naftazone or a kind of its pharmaceutical composition of pharmaceutically acceptable salt, wherein :-substantially discharge Naftazone or a kind of its first pulse of pharmaceutically acceptable salt, and-about 3 hours to about 8 hours release Naftazones or a kind of its at least one additional pulse of pharmaceutically acceptable salt after described take orally at once after oral described pharmaceutical composition.