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ERYTROPOETYNA DO ZASTOSOWANIA W LECZENIU RAN LUB TRANSPLANTACJI KOMÓREK
专利权人:
Bader
发明人:
Bader Augustinus
申请号:
PL10005293
公开号:
PL2233150T3
申请日:
2004.12.30
申请国别(地区):
PL
年份:
2017
代理人:
摘要:
Use of hematopoietic growth factors (I), especially erythropoietin (EPO), thrombopoietin (TPO) or their derivatives, analogs and fragments, to prepare a composition for structural regeneration of tissue, is new. Independent claims are also included for the following: (1) similar use of an EPO-inducing factor (II); (2) carrier structure containing at least one (I) or (II); (3) preparing the structure of (2); and (4) composition comprising cells (A) that have been pretreated, in vitro, with (I). ACTIVITY : Hepatotropic; Osteopathic; Cardiant; Ophthalmological; Uropathic; Antiinflammatory; Antiulcer; Vulnerary; Neuroprotective. Part of the liver was removed from pigs, then the animals (a) given no treatment; (b) treated locally with 10 4>; units EPO and a fibrin glue; or (c) treated systemically with 10 4>; units EPO on days 0, 3, 7 and 11. After 14 days, the mean liver volume (ml) was (a) 892; (b) 894 and (c) 1073, and liver weight (g) was (a) 1001; (b) 1027 and (c) 1249; where these results for (c) are statistically significant at p less than 0.05. MECHANISM OF ACTION : Promoting regrowth of tissue.
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