Disclosed are a caspofungin analog and applications thereof. Said caspofungin 5 analog is a compound having a structure as indicated in Formula (4), or pharmaceutical acceptable slats thereof. Rl can be chosen from hydroxyl, benzyloxy, phenoxy, substituted phenoxy, or substituted benzyloxy. R2, R3, R4, R5 can be chosen from hydrogen, C1-C6 alkyl, C1-C6 alkoxy, hydroxyl, benzyloxyphenyl, substituted benzyloxyphenyl, nitro, fluorine, chlorine, bromine, or iodine. Also 10 disclosed are a preparation method for and applications of said compound.
