Adilah Bahadoor,Alfredo C. Castro,Lawrence K. Chan,Gregg F. Keaney,Marta Nevalainen,Vesa Nevalainen,Stephane Peluso,Daniel A. Snyder,Thomas T. Tibbitts
申请号:
US15136817
公开号:
US20170119734A1
申请日:
2016.04.22
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Provided herein are tetrazolone FASN inhibitors of the formula (I):or a pharmaceutically acceptable form thereof, wherein the variables RA, RB and RC are defined herein.Also provided herein are pharmaceutical compositions of the compounds provided herein as well as methods of their use for the treatment of various disorders such as hyperproliferative disorders, inflammatory disorders, obesity-related disorders and microbial infections.